Eagles will face Jaguars in London without Saquon Barkley and DeVonta Smith

Philadelphia will be without running back Saquon Barkley and wide receiver DeVonta Smith when the Eagles meet the Jacksonville Jaguars in London on Sunday. The Eagles listed both starters out with hamstring injuries; Barkley was hurt in last week’s loss to the Rams, while Smith has missed two straight games. Five Eagles in total were ruled out, including wide receiver Hollywood Brown, safety Marcus Epps and center Drew Kendall. The absences reshape an offense already adjusting to major personnel changes. Philadelphia released veteran quarterback Andy Dalton on Friday, leaving Jalen Hurts as the starter, Tanner McKee as the backup and rookie Cole Payton as the developmental third quarterback, NFL.com reported. The team also signed running back Dameon Pierce to its active roster this week. With Barkley unavailable, Will Shipley is expected to take on a larger role, with Pierce also available in the backfield. The game at Tottenham Hotspur Stadium is scheduled for 9:30 a.m. ET Sunday, Oct. 11. Philadelphia enters at 2–2; Jacksonville is 3–1. The Eagles’ official matchup page lists the full injury report and broadcast information. The status report confirms who is unavailable, but it does not provide a timetable for Barkley’s or Smith’s return beyond the London game. Photo: Saquon Barkley during Philadelphia’s public practice on Aug. 25, 2026. Photo by Kiel Leggere/Philadelphia Eagles; used here as an illustrative team image, not a picture from the London trip. Sources: [NFL.com, roster and injury update](https://www.nfl.com/news/eagles-release-veteran-qb-andy-dalton-saquon-barkley-to-miss-london-game-vs-jaguars), [Philadelphia Eagles, Week 5 injury report](https://www.philadelphiaeagles.com/news/eagles-at-jaguars-injury-report-2026-nfl-week-5-london-international-game-saquon-barkley-devonta-smith), [Eagles-Jaguars game details](https://www.philadelphiaeagles.com/news/how-to-watch-stream-and-listen-eagles-at-jaguars-2026-nfl-week-5-london-international-game-cooper-dejean-trevor-lawrence-travis-hunter), and [official Eagles photo gallery](https://www.philadelphiaeagles.com/photos/eagles-public-practice-photo-gallery-august-25-2026).